Higashikuni Lab
Higashikuni Lab
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Synthetic Cardiology
Synthetic Cardiology
Creating novel gene and cell therapies that enable automatic reversal of aging phenotypes and maintenance of homeostasis by introducing multimodal sense-and-respond capabilities into living cells.
Novel Therapeutic Strategy for Cardiovascular Disease
Based on our basic research findings and clinical experience, we will discuss next-generation therapeutic strategy for cardiovascular disease.
Nov 11, 2023 9:00 AM — 6:00 PM
Tokyo, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Diabetes in Cardiovascular Medicine
Synthetic biology approach for the treatment of diabetes and cardiovascular disease will be discussed.
Sep 6, 2022 7:00 PM — 8:30 PM
Tokyo, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Hyperuricemia in Cardiovascular Medicine
Our basic research findings provide new insight into therapeutic strategy for hyperuricemia in patients with cardiovascular disease.
May 26, 2022 7:00 PM — 8:00 PM
Tokyo, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Next-Generation Therapeutic Platforms in Cardiovascular Medicine
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Next-Generation Gene Therapy for Heart Failure
Our next-generation gene therapy for heart failure enables personalized medicine at cellular level.
Jul 26, 2020 11:00 PM — Aug 2, 2020 8:00 AM
Kyoto, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Next-Generation Therapeutic Platforms in Cardiovascular Medicine
The Present and the Future of Cardiovascular Medicine
Jun 3, 2020 11:00 PM — Jun 6, 2020 8:00 AM
Kobe, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Advancing CRISPR-Based Programmable Platforms beyond Genome Editing in Mammalian Cells
Human diseases are caused by dysregulation of cellular biological programs that are encoded in DNA. Unveiling the endogenous programs …
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Timothy K. Lu
Project
Project
DOI
Single-Nucleotide-Resolution Computing and Memory in Living Cells
The ability to process and store information in living cells is essential for developing next-generation therapeutics and studying …
Fahim Farzadfard
,
Nava Gharaei
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Giyoung Jung
,
Jicong Cao
,
Timothy K. Lu
Project
Project
DOI
Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates
Antimicrobial peptides (AMPs) constitute promising alternatives to classical antibiotics for the treatment of drug-resistant …
Marcelo D. T. Torres
,
Cibele N. Pedron
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Robin M. Kramer
,
Marlon H. Cardoso
,
Karen G. N. Oshiro
,
Octavio L. Franco
,
Pedro I. Silva Junior
,
Fernanda D. Silva
,
Vani X. Oliveira Junior
,
Timothy K. Lu
,
Cesar de la Fuente-Nunez
Project
DOI
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