Higashikuni Lab
Higashikuni Lab
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Homeostatic Inflammation
Diabetes in Cardiovascular Medicine
Synthetic biology approach for the treatment of diabetes and cardiovascular disease will be discussed.
Sep 6, 2022 7:00 PM — 8:30 PM
Tokyo, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Give a Leg Up: Screening for Peripheral Artery Disease after Acute Myocardial Infarction
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Wenhao Liu, M.D.
,
Masataka Sata
Project
DOI
Hyperuricemia in Cardiovascular Medicine
Our basic research findings provide new insight into therapeutic strategy for hyperuricemia in patients with cardiovascular disease.
May 26, 2022 7:00 PM — 8:00 PM
Tokyo, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Project
Homeostatic Inflammation in Heart Disease
How inflammation is regulated in the heart and contributes to the transition from adaptive cardiac hypertrophy to heart failure will be discussed.
Mar 13, 2022 9:00 AM — 12:00 PM
Kobe, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Project
Aging in Cardiovascular Medicine
Aging and cardiovascular disease will be discussed.
Jan 25, 2022 7:00 PM — 8:00 PM
Tokyo, Online
Yasutomi Higashikuni, M.D., Ph.D., FESC
Project
Pathogenic Basis of Thromboinflammation and Endothelial Injury in COVID-19: Current Findings and Therapeutic Implications
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Wenhao Liu, M.D.
,
Takumi Obana
,
Masataka Sata
Project
DOI
Biodegradable Extremely-Small-Diameter Vascular Graft Made of Silk Fibroin can be Implanted in Mice
Aim, Synthetic vascular grafts are widely used in surgical revascularization, mainly for medium- to large-sized vessels. However, …
Kimie Tanaka
,
Daiju Fukuda
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Yoichiro Hirata
,
Issei Komuro
,
Toshiki Saotome
,
Yoshihiro Yamashita
,
Tetsuo Asakura
,
Masataka Sata
Project
DOI
Activation of Toll-Like Receptor 9 Impairs Blood Flow Recovery After Hind-Limb Ischemia
Background, Peripheral artery disease causes significant functional disability and results in impaired quality of life. Ischemic tissue …
Sachiko Nishimoto
,
Kunduziayi Aini
,
Daiju Fukuda
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Kimie Tanaka
,
Yoichiro Hirata
,
Shunsuke Yagi
,
Kenya Kusunose
,
Hirotsugu Yamada
,
Takeshi Soeki
,
Michio Shimabukuro
,
Masataka Sata
Project
DOI
Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis
Background Toll-like receptor ( TLR ) 9 recognizes bacterial DNA , activating innate immunity, whereas it also provokes inflammation in …
Daiju Fukuda
,
Sachiko Nishimoto
,
Kunduziayi Aini
,
Atsushi Tanaka
,
Tsuyoshi Nishiguchi
,
Joo-Ri Kim-Kaneyama
,
Xiao-Feng Lei
,
Kiyoshi Masuda
,
Takuya Naruto
,
Kimie Tanaka
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Yoichiro Hirata
,
Shunsuke Yagi
,
Kenya Kusunose
,
Hirotsugu Yamada
,
Takeshi Soeki
,
Issei Komuro
,
Takashi Akasaka
,
Michio Shimabukuro
,
Masataka Sata
Project
DOI
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance
Obesity stimulates chronic inflammation in adipose tissue, which is associated with insulin resistance, although the underlying …
Sachiko Nishimoto
,
Daiju Fukuda
,
Yasutomi Higashikuni, M.D., Ph.D., FESC
,
Kimie Tanaka
,
Yoichiro Hirata
,
Chie Murata
,
Joo-Ri Kim-Kaneyama
,
Fukiko Sato
,
Masahiro Bando
,
Shunsuke Yagi
,
Takeshi Soeki
,
Tetsuya Hayashi
,
Issei Komuro
,
Hiroshi Sakaue
,
Michio Shimabukuro
,
Masataka Sata
Project
DOI
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